Personal research done on a number of cases with chronic lupus erythematosus
April 1, 2010
| Abstract Title: | Personal research done on a number of cases with chronic lupus erythematosus |
| Authors: | Victor Neamtiu, Floare Folescu |
| Affiliation: | Dermatology Department, “Vasile Goldis” Western University of Arad, Romania |
| Abstract text: | The localized Chronic Lupus Erythematosus is a form of lupus erythematosus, characterized by the presence of skin lesions with a chronic evolution, rarely accompanied by visceral damage. The objectives are to determine some favourable facts in LEC occurrence; evolution and prognosis at LEC sick people. Materials and methods. The study was made over an eight year period (2001-2008) at Municipal Hospital, Dermatology and Venereology department in Arad over a group of 213 people from which a series of data regarding the frequency and some considerations of this affection were issued. Conclusions. Lupus erythematosus is a complex disease with numerous forms of manifestation and framed in the collagen diseases. These diseases have as a histological cause the fibroma degenerescence of the fundamental substance of the conjunctive tissue. The disease is more frequent or it is aggravating in the sunny season and this thing comes out from anamnesis and the clinical examination (the exposed teguments to the ultraviolet rays). In the studied cases, the symptoms started in the warm season at a 78.12% of the sick people. At sick women infested with lupus higher levels of oestrogens metabolites was noticed compared with the valued met at normal women and the administration of oral contraceptives worsen the disease. From the total of 146 women with LEC studied, 52 of the cases are represented by women in their fertile period among which 68.04% used oral contraceptives. The main complications of LEC are coetaneous and their implications are mainly aesthetic. Thus, mutilations of the acral areas, irreversible alopecia of the scalp, slowly curable chronic coetaneous ulcerations and the development of spin cellular carcinoma in the affected areas. The vital prognosis is good, only with a little percentage (7%) among the patients developing a systemic form. |
| Keywords: | Chronic Lupus Erythematosus, oestrogens metabolites, oral contraceptives, aesthetic complications |
| Presentation type: | Poster |
| Correspondence: | no. 10 M. Viteazu Sq., Arad, Romania |
| Email: | victor_neamtiu@yahoo.com |
About The Author
