D-dimers: their´s place in ischemic stroke initial evaluation, in the Emergency Department

September 18, 2016

D-dimers: their´s place in ischemic stroke initial evaluation, in the Emergency Department

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Title:	D-dimers: their´s place in ischemic stroke initial evaluation, in the Emergency Department
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Article_Title:	D-dimers: their´s place in ischemic stroke initial evaluation, in the Emergency Department
Authors:	Radu Jipa, Daniela Motoc, Bogdan Pitis
Affiliation:	‘’Vasile Goldis’’, Western University of Arad, Faculty Of Medicine Pharmacy And Dentistry
Abstract:	The ischemic stroke represents one of the most frequent pathology patients present with in the Emergency Department (ED). Because of the wide range of simptoms, sometimes the diagnosis process requires significant time and resources, not allways available in a busy E.D. To reduce the necessary time to establish a diagnosis, apart of physical exam and CT-imaging, new methods and protocols could be proposed. The value of D-dimers represent a tool that can be used to assess the probability of the presence of new thrombuses, including cerebral. This preliminary study investigates the utility of the use of D-dimers in clinical practice and the posibility to be integrated in a more elaborate protocole focused on ischemic stroke.
Keywords:	D-dimers, ishemic stroke, Emergency Department
References:	1. D-dimers increase in acute ischemic stroke patients with the large artery occlusion, but do not depend on the time of artery recanalization. Skoloudík D1, Bar M, Sanák D, Bardon P, Roubec M, Langová K, Herzig R, Kanovský P., Semin Vasc Med. 2005 Nov;5(4):379-86., J Thromb Thrombolysis. 2010 May;29(4):477-82. doi: 10.1007/s11239-009-0372-9. 2. D-dimer testing in ischemic stroke and cerebral sinus and venous thrombosis. Squizzato A1, Ageno W. Semin Vasc Med. 2005 Nov;5(4):379-86. 3. Plasma D-Dimer Levels Are Associated with Stroke Subtypes and Infarction Volume in Patients with Acute Ischemic Stroke. Wen-Jie Zi, Jie Shuai, Published: January 20, 2014, http://dx.doi.org/10.1371/journal.pone.0086465 4. Plasma Measurement of D-Dimer Levels for the Early Diagnosis of Ischemic Stroke Subtypes, Walter Ageno, MD; Sergio Finazzi, MD; Luigi Steidl, MD; Maria Grazia Biotti, MD; Valentina Mera, MD; GianVico Melzi d’Eril, MD; Achille Venco, MD, [+] Author Affiliations, Arch Intern Med. 2002;162(22):2589-2593. doi:10.1001/archinte.162.22.2589
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Article Title:	D-dimers: their´s place in ischemic stroke initial evaluation, in the Emergency Department
Authors:	Radu Jipa, Daniela Motoc, Bogdan Pitis
Affiliation:	‘’Vasile Goldis’’, Western University of Arad, Faculty Of Medicine Pharmacy And Dentistry
Abstract:	The ischemic stroke represents one of the most frequent pathology patients present with in the Emergency Department (ED). Because of the wide range of simptoms, sometimes the diagnosis process requires significant time and resources, not allways available in a busy E.D. To reduce the necessary time to establish a diagnosis, apart of physical exam and CT-imaging, new methods and protocols could be proposed. The value of D-dimers represent a tool that can be used to assess the probability of the presence of new thrombuses, including cerebral. This preliminary study investigates the utility of the use of D-dimers in clinical practice and the posibility to be integrated in a more elaborate protocole focused on ischemic stroke.
Keywords:	D-dimers, ishemic stroke, Emergency Department
References:	1. D-dimers increase in acute ischemic stroke patients with the large artery occlusion, but do not depend on the time of artery recanalization. Skoloudík D1, Bar M, Sanák D, Bardon P, Roubec M, Langová K, Herzig R, Kanovský P., Semin Vasc Med. 2005 Nov;5(4):379-86., J Thromb Thrombolysis. 2010 May;29(4):477-82. doi: 10.1007/s11239-009-0372-9. 2. D-dimer testing in ischemic stroke and cerebral sinus and venous thrombosis. Squizzato A1, Ageno W. Semin Vasc Med. 2005 Nov;5(4):379-86. 3. Plasma D-Dimer Levels Are Associated with Stroke Subtypes and Infarction Volume in Patients with Acute Ischemic Stroke. Wen-Jie Zi, Jie Shuai, Published: January 20, 2014, http://dx.doi.org/10.1371/journal.pone.0086465 4. Plasma Measurement of D-Dimer Levels for the Early Diagnosis of Ischemic Stroke Subtypes, Walter Ageno, MD; Sergio Finazzi, MD; Luigi Steidl, MD; Maria Grazia Biotti, MD; Valentina Mera, MD; GianVico Melzi d’Eril, MD; Achille Venco, MD, [+] Author Affiliations, Arch Intern Med. 2002;162(22):2589-2593. doi:10.1001/archinte.162.22.2589
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