Nowadays classification of gastric dysplasia
April 18, 2010
| Abstract Title: | Nowadays classification of gastric dysplasia |
| Authors: | Papiu Horatiu¹, Dumnici Alexandru¹, Oniţa M. ², Sofronie S.¹, Munteanu Armando3, Aiordăchioae Gigi¹, Albu Anastasia², Ţepeş Viorel² |
| Affiliation: | ¹”Vasile Goldis” Western University Arad, Romania ²Clinic Municipal Hospital Arad, Romania 3Life Sciences Institute, “Vasile Goldis” Western University Arad, Romania |
| Abstract text: | Gastric mucosal dysplasias are the most frequent premalignant gastric lesions. The study of these lesions is particularly important for prevention and early detection of gastric cancer. Classifications are presented with the latest and most practical application. These are the classification of dysplasia in three degrees – light, medium and severe, and the other grouping the dysplasia into two classes – low grade and high grade. It is important to notice that Vienna Classification place low grade dysplasia in Group III of gastrointestinal malignancies and high grade dysplasia with carcinoma in situ in Group IV. A total of 3736 patients were performed histopathological examinations of the gastric mucosa, highlighted a number of 598 (16%) cases with gastric dysplasia. Of these, mild dysplasia was found in 122 (20.40%), medium dysplasia in 245 (40.96%) and severe dysplasia in 231 (38.64%). Light and medium injuries are included in the low group, representing 367 cumulative cases, 61.36%, positioned in Class III of the Vienna Classification. Severe dysplasia, which is present in the remaining 38.64% of cases, is included in group IV of this classification. Most of dysplasias were associated with other pathological changes of gastric mucosa, particularly a significant percentage of associations of severe dysplasia with invasive carcinoma and in situ carcinoma. These findings suggest that high-grade dysplasia is a lesion with high malignant potential. Vienna Classification recommendations emphasize that severe dysplasia and noninvasive gastric cancer (in situ) indicates the need for local endoscopic or surgical excision of these lesions. |
| Keywords: | premalignant gastric lesions, gastric dysplasia, classification, gastric cancer |
| Presentation type: | Poster |
| Correspondence: | no. 1 Feleacului St., Arad, Romania |
| Email: | horatiuspapiu@yahoo.com |
About The Author
