Topical application of Silybum marianum extract

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Article Title:	Topical application of Silybum marianum extract
Authors:	Pálma Fehér, Miklós Vecsernyés, Ferenc Fenyvesi, Judit Váradi, Tímea Kiss, Zoltán Újhelyi, Katalin Nagy, Ildikó Bácskay*
Affiliation:	Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Debrecen, Hungary
Abstract:	Most of the cosmeceuticals with herbal origin have strong antioxidant activity. Because oxidative stress is one of the major mechanisms for skin aging and dermatologic conditions, phytochemicals with proven antioxidant activity, such as silibinin, could be useful for treating many dermatologic conditions as well as skin aging. Silibinin is a flavonolignan compound from Silybum marianum that possesses strong antioxidant activity and also modulates many molecular changes caused by xenobiotics and ultraviolet radiation to protect the skin (Singh et al, 2009). Our aim was to give a brief description of the topical use of the active components of Silybum marianum.
Keywords:	cosmeceuticals, topical application, Silybum marianum, silymarin, skin disorders
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*Correspondence:	Ildikó Bácskay*, Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Debrecen, Hungary