TESTING THE EFFECTIVENESS OF INHERENT ANTIMICROBIAL PRESERVATIVES OF A COSMETIC PRODUCT WITH ORGANIC ACTIVE INGREDIENTS


TESTING THE EFFECTIVENESS OF INHERENT ANTIMICROBIAL PRESERVATIVES OF A COSMETIC PRODUCT WITH ORGANIC ACTIVE INGREDIENTS

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Title: TESTING THE EFFECTIVENESS OF INHERENT ANTIMICROBIAL PRESERVATIVES OF A COSMETIC PRODUCT WITH ORGANIC ACTIVE INGREDIENTS
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Article_Title: TESTING THE EFFECTIVENESS OF INHERENT ANTIMICROBIAL PRESERVATIVES OF A COSMETIC PRODUCT WITH
ORGANIC ACTIVE INGREDIENTS
Authors: Darin Salman1, Carmen Popescu2*, Georgeta Coneac3, Candice Luana Popescu,4Dumitru Lupuleasa1
Affiliation: 1University of Medicine and Pharmacy‘Carol Davila’, Bucharest, Romania, 2WestUniversity ‘VasileGoldis’, Arad, Romania, 3University of Medicine and Pharmacy‘Victor Babes’, Timisoara, Romania, 4PharmaciesSensiblu, Bucharest, 5 District,
Abstract: In this study we formulated, developed and tested body care milk that contains two active ingredients of plant origin from Organic Agriculture, obtained by cold pressing, namely: vegetable greasy oil from sea buckthorn [Hippophaerhamnoides.L.] and greasy oil from flaxseeds [Linumusitatissimum.L.], with coenzyme Q10.
The purpose of this paper is to demonstrate the antimicrobial efficacy of a cosmetic product with its own antimicrobial properties, product what contained these two organic active ingredients.
Milk Body Care formula contains no preservatives in the preparation and therefore in this study we aim to demonstrate the antimicrobial efficacy of cosmetic product components in accordance with the requirements of the European Pharmacopoeia monograph ed. 7-a / 2010.
Keywords: organic active ingredients, cold pressing, antimicrobial efficacy
References: 1. BakhtJehan; Ali Huma; Khan Mubarak Ali; et al, Antimicrobial activities of different solvents extracted samples of Linumusitatissimum by disc diffusion method;Publishedin:AFRICAN JOURNAL OF BIOTECHNOLOGY Volume: 10 Issue: 85 Pages: 19825-19835 DOI: 10.5897/AJB11.229 Published: DEC 28 2011.
2. Cakir A. Essential oil and fatty acid composition of the fruits of Hippophaerhamnoides L. (Sea Buckthorn) and Myrtuscommunis L. from Turkey. BiochemSystEcol . 2004; 32:809-816.
3. Cundell, AM, Chatellier, S, Schumann, P, Lilischkis, R. Equivalence of Quality Control Strains of Microorganisms Used in the Compendial Microbiological Tests: Are National Culture Collection Strains Identical?.PDA J Pharm Sci Tech. 2009.Meyer BK, Ni X, Hu B, Shi L.
4. European Pharmacopeia, Efficacy of antimicrobial preservatives, 7th edition, Council of Europe, Strasbourg, 2010.
5. Gaurav Kaithwas, AlokMukerjee, P Kumar, Dipak K Majumdar, Department of Pharmaceutical Sciences, F.H.M.S, Allahabad Agricultural Institute-Deemed University, Allahabad 211007, U.P., India, Linumusitatissimum (linseed/flaxseed) fixed oil: antimicrobial activity and efficacy in bovine mastitis, Inflammopharmacology 02/2011; Volume 19(1):45-52. DOI:10.1007/s10787-010-0047-3
6. Guliyev VB, Gul M, Yildirim A. Hippophaerhamnoides L.: chromatographic methods to determine chemical composition, use in traditional medicine and pharmacological effects. J Chromatogr B AnalytTechnol Biomed Life Sci. 2004; 812:291-307.
7. Hibasami H, Mitani A, Katsuzaki H, Imai K, Yoshioka K, Komiya T. Isolation of five types of flavonol from seabuckthorn ( Hippophaerhamnoides ) and induction of apoptosis by some of the flavonols in human promyelotic leukemia HL-60 cells. Int J Mol Med. 2005; 15:805-809.
8. Kasparaviciene G, Briedis V, Ivanauskas L. Influence of sea buckthorn oil production technology on its antioxidant activity [in Lithuanian]. Medicina (Kaunas). 2004; 40:753-757.
9. Luhua Z, Ying T, Zhengyu Z, Guangji W. Determination of alpha-tocopherol in the Traditional Chinese Medicinal preparation Sea buckthorn oil capsule by non-aqueous reversed phase-HPLC. Chem Pharm Bull (Tokyo). 2004; 52:150-152.
10. McDonald MI, Graham I, Harvey KJ, Sinclair A (1981) Antibacterial activity of hydrolysed linseed oil and linolenic acid against methicillin-resistant Staphylococcus aureus. Lancet 2:1056.
11. NandPratibha; DrabuSushma; Gupta RajinderK.,Antimicrobial Investigation of Linumusitatissimum for the Treatment of Acne; NATURAL PRODUCT COMMUNICATIONS Volume: 6 Issue: 11 Pages: 1701-1704 Published: NOV 2011.
12. Negi P, Chauhan A, Sadia G, Rohinishree Y, Ramteke R. Antioxidant and antibacterial activities of various seabuckthorn (Hippophaerhamnoides L.) seed extracts. Food Chem . 2005; 92:119-124.
13. Pop G.; Laza A.; Dragomirescu A.; et al.,Researches regarding skin anti-photoaging effect of Linumusitatissimum L. oil by using an in vivo skin imagistic dermatologic evaluation, PLANTA MEDICA Volume: 77 Issue: 12 Pages: 1369-1370 Published: AUG 2011.
14. Puupponen-Pimia R, Nohynek L, Meier C, et al. Antimicrobial properties of phenolic compounds from berries. J Appl Microbial, 2001; 90:494-507.
15. Rosch D, Krumbein A, Mugge C, Kroh LW. Structural investigations of flavonolglycosides from sea buckthorn (Hippophaerhamnoides )pomace by NMR spectroscopy and HPLC-ESI-MS(n). J Agric Food Chem. 2004; 52:4039-4046.
16. Rosch D, Mugge C, Fogliano V, Kroh LW. Antioxidant oligomericproanthocyanidins from sea buckthorn (Hippophaerhamnoides)Pomace. J Agric Food Chem. 2004; 52:6712-6718.
17. SaadiaChaman, Nawazish-I-Husain Syed, Zeeshan Danish, Farrakh Zia Khan, University College of Pharmacy, University of the Punjab, Lahore, Pakistan; Phytochemical analysis, antioxidant and antibacterial effects of sea buckthorn berries.Pakistan journal of pharmaceutical sciences (Impact Factor: 0.95). 07/2011; 24(3):345-51.
18. United States Pharmacopeia, USP 34-NF29, US Pharmacopeia, Rockville, Maryland, USA, 2010.
Read_full_article: pdf/vol15/iss1-4/20 JMA 2012 Popescu Carmen – TESTAREA EFICACITATII CONSERVANTE ANTIMICROBIENE.pdf
Correspondence: popescu_carmen88@yahoo.com,

Read full article
Article Title: TESTING THE EFFECTIVENESS OF INHERENT ANTIMICROBIAL PRESERVATIVES OF A COSMETIC PRODUCT WITH
ORGANIC ACTIVE INGREDIENTS
Authors: Darin Salman1, Carmen Popescu2*, Georgeta Coneac3, Candice Luana Popescu,4Dumitru Lupuleasa1
Affiliation: 1University of Medicine and Pharmacy‘Carol Davila’, Bucharest, Romania, 2WestUniversity ‘VasileGoldis’, Arad, Romania, 3University of Medicine and Pharmacy‘Victor Babes’, Timisoara, Romania, 4PharmaciesSensiblu, Bucharest, 5 District,
Abstract: In this study we formulated, developed and tested body care milk that contains two active ingredients of plant origin from Organic Agriculture, obtained by cold pressing, namely: vegetable greasy oil from sea buckthorn [Hippophaerhamnoides.L.] and greasy oil from flaxseeds [Linumusitatissimum.L.], with coenzyme Q10.
The purpose of this paper is to demonstrate the antimicrobial efficacy of a cosmetic product with its own antimicrobial properties, product what contained these two organic active ingredients.
Milk Body Care formula contains no preservatives in the preparation and therefore in this study we aim to demonstrate the antimicrobial efficacy of cosmetic product components in accordance with the requirements of the European Pharmacopoeia monograph ed. 7-a / 2010.
Keywords: organic active ingredients, cold pressing, antimicrobial efficacy
References: 1. BakhtJehan; Ali Huma; Khan Mubarak Ali; et al, Antimicrobial activities of different solvents extracted samples of Linumusitatissimum by disc diffusion method;Publishedin:AFRICAN JOURNAL OF BIOTECHNOLOGY Volume: 10 Issue: 85 Pages: 19825-19835 DOI: 10.5897/AJB11.229 Published: DEC 28 2011.
2. Cakir A. Essential oil and fatty acid composition of the fruits of Hippophaerhamnoides L. (Sea Buckthorn) and Myrtuscommunis L. from Turkey. BiochemSystEcol . 2004; 32:809-816.
3. Cundell, AM, Chatellier, S, Schumann, P, Lilischkis, R. Equivalence of Quality Control Strains of Microorganisms Used in the Compendial Microbiological Tests: Are National Culture Collection Strains Identical?.PDA J Pharm Sci Tech. 2009.Meyer BK, Ni X, Hu B, Shi L.
4. European Pharmacopeia, Efficacy of antimicrobial preservatives, 7th edition, Council of Europe, Strasbourg, 2010.
5. Gaurav Kaithwas, AlokMukerjee, P Kumar, Dipak K Majumdar, Department of Pharmaceutical Sciences, F.H.M.S, Allahabad Agricultural Institute-Deemed University, Allahabad 211007, U.P., India, Linumusitatissimum (linseed/flaxseed) fixed oil: antimicrobial activity and efficacy in bovine mastitis, Inflammopharmacology 02/2011; Volume 19(1):45-52. DOI:10.1007/s10787-010-0047-3
6. Guliyev VB, Gul M, Yildirim A. Hippophaerhamnoides L.: chromatographic methods to determine chemical composition, use in traditional medicine and pharmacological effects. J Chromatogr B AnalytTechnol Biomed Life Sci. 2004; 812:291-307.
7. Hibasami H, Mitani A, Katsuzaki H, Imai K, Yoshioka K, Komiya T. Isolation of five types of flavonol from seabuckthorn ( Hippophaerhamnoides ) and induction of apoptosis by some of the flavonols in human promyelotic leukemia HL-60 cells. Int J Mol Med. 2005; 15:805-809.
8. Kasparaviciene G, Briedis V, Ivanauskas L. Influence of sea buckthorn oil production technology on its antioxidant activity [in Lithuanian]. Medicina (Kaunas). 2004; 40:753-757.
9. Luhua Z, Ying T, Zhengyu Z, Guangji W. Determination of alpha-tocopherol in the Traditional Chinese Medicinal preparation Sea buckthorn oil capsule by non-aqueous reversed phase-HPLC. Chem Pharm Bull (Tokyo). 2004; 52:150-152.
10. McDonald MI, Graham I, Harvey KJ, Sinclair A (1981) Antibacterial activity of hydrolysed linseed oil and linolenic acid against methicillin-resistant Staphylococcus aureus. Lancet 2:1056.
11. NandPratibha; DrabuSushma; Gupta RajinderK.,Antimicrobial Investigation of Linumusitatissimum for the Treatment of Acne; NATURAL PRODUCT COMMUNICATIONS Volume: 6 Issue: 11 Pages: 1701-1704 Published: NOV 2011.
12. Negi P, Chauhan A, Sadia G, Rohinishree Y, Ramteke R. Antioxidant and antibacterial activities of various seabuckthorn (Hippophaerhamnoides L.) seed extracts. Food Chem . 2005; 92:119-124.
13. Pop G.; Laza A.; Dragomirescu A.; et al.,Researches regarding skin anti-photoaging effect of Linumusitatissimum L. oil by using an in vivo skin imagistic dermatologic evaluation, PLANTA MEDICA Volume: 77 Issue: 12 Pages: 1369-1370 Published: AUG 2011.
14. Puupponen-Pimia R, Nohynek L, Meier C, et al. Antimicrobial properties of phenolic compounds from berries. J Appl Microbial, 2001; 90:494-507.
15. Rosch D, Krumbein A, Mugge C, Kroh LW. Structural investigations of flavonolglycosides from sea buckthorn (Hippophaerhamnoides )pomace by NMR spectroscopy and HPLC-ESI-MS(n). J Agric Food Chem. 2004; 52:4039-4046.
16. Rosch D, Mugge C, Fogliano V, Kroh LW. Antioxidant oligomericproanthocyanidins from sea buckthorn (Hippophaerhamnoides)Pomace. J Agric Food Chem. 2004; 52:6712-6718.
17. SaadiaChaman, Nawazish-I-Husain Syed, Zeeshan Danish, Farrakh Zia Khan, University College of Pharmacy, University of the Punjab, Lahore, Pakistan; Phytochemical analysis, antioxidant and antibacterial effects of sea buckthorn berries.Pakistan journal of pharmaceutical sciences (Impact Factor: 0.95). 07/2011; 24(3):345-51.
18. United States Pharmacopeia, USP 34-NF29, US Pharmacopeia, Rockville, Maryland, USA, 2010.
*Correspondence: popescu_carmen88@yahoo.com,