ENDOMETRIAL HISTOPATHOLOGY FINDINGS IN POSTMENOPAUSAL WOMEN

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Article Title:	ENDOMETRIAL HISTOPATHOLOGY FINDINGS IN POSTMENOPAUSAL WOMEN
Authors:	Corina Ülgüt, Lucian Paiusan, Gheorghe Furau, Casiana Stanescu
Affiliation:	¹As.Univ.Drd., Resident Doctor, Pathology Departament, County Emergency Hospital Arad “Vasile Goldis” Western University Arad, Faculty of Medicine, Morphopathology Department ² Conf.Univ., Head of Departament, Pathology Departament, County Emergency Hospital Arad “Vasile Goldis” Western University Arad, Faculty of Medicine, Morphopathology Department ³Conf.Univ., Head of Departament, Obstetric and Gynecology Departament, County Emergency Hospital Arad “Vasile Goldis” Western University Arad, Faculty of Medicine
Abstract:	Abnormal uterine bleeding is a common gynaecological complaint, an important problem of menopause women’s health. Post menopausal bleeding is generally regarded as an ominous and serious alarm of genital pathologies. The term “post menopausal bleeding” generally implies bleeding from the uterus and it is essentially the only bleeding of importance at the postmenopausal age. The current study was carried out to evaluate various causes of postmenopausal bleeding based on histopathology, and the percentage of various benign, premalignant and malignant endometrial and cervical lesions in post menopausal bleeding.This retrospective study of endometrial pathology in postmenopausal bleeding was conducted by the Pathology Departament of the Obstetric and Gynecology Hospital of Arad, Romania, between January 2010 – December 2014. We examined a number of 258 postmenopausal women that came with abnormal uterine bleeding. Exclusion criteria were premature menopause whether surgical or natural, age less than 55 years and patients on hormone replacement therapy. In our study atrophy of the endometrium and chronic hypotrophic endometritis was the predominant finding in the women in the postmenopausal period (41,85%). The incidence of benign endometrial polyps (12,02%), adenocarcinoma of the endometrium was found in 27,52% of the samples. Endometrial hyperplasia, with or without atypia, is considered to be a precursor of carcinoma [13] and was found in about 15,50% of women in the present study. Postmenopausal bleeding is a symptom of varied etiologies and is not always because of malignant conditions. Therefore, the histologic examination has to be careful in order to find benign, premalignant and malignant lesions. An accurate diagnosis will make it much easier to counsel the patient confidently about the appropriate course of action and facilitate in carrying out the proper treatment plan that will benefit the patient.
Keywords:	endometrial atrophy, benign endometrial polyps, endometrioid carcinoma
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