Assessment of proinflammatory status in psoriatic arthritis versus rheumatoid arthritis
| Abstract Title: | Assessment of proinflammatory status in psoriatic arthritis versus rheumatoid arthritis |
| Authors: | Camelia Ciacli*, Simona Borta**, Maria Puschita* |
| Affiliation: | *”Vasile Goldis” Western University, Arad, Romania **Clinical County Hospital Arad, Romania |
| Abstract text: | Objectives: The aim of this study was to investigate the concentration of Th1 types cytokines (IL -1, IL-6, and TNF-alpha) in the peripheral blood of patients with psoriatic arthritis versus rheumatoid arthritis and healthy individuals. Method: In this study we enrolled twenty-six patients diagnosed with psoriatic arthritis, twenty patients diagnosed with rheumatoid arthritis and twenty-seven controls were included. The pro-inflammatory cytokines levels blood and fluid were quantified by using ELISA method (Endogen, Woburg, MA, USA). Results: In this study we observed that peripheral blood concentrations were higher in patients with psoriatic arthritis than controls, and lower than patients with rheumatoid arthritis. Conclusion: This study has detected higher levels of pro-inflammatory cytokines in both arthritis, psoriatic and rheumatoid, so reflecting the proinflammatory status in these diseases, and the increase in pro-inflammatory cytokines serum level is strongly positive related to the activity of diseases in patients with psoriatic arthritis and rheumatoid arthritis. |
| Keywords: | psoriasis arthritis, rheumatoid arthritis, pro-inflammatory cytokines, Th1 types cytokines, proinfla |
| Presentation type: | Poster |
| Correspondence: | no. 7 Herodot St., Arad, Romania |
| Email: | cciacli@yahoo.com |
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