Juvenile idiopathic arthritis – Case Study

Abstract Title: Juvenile idiopathic arthritis – Case Study
Authors: Leordean Viorica, Dorin Lazar
Affiliation: “Vasile Goldis” Western University Arad, Romania
Abstract text: Juvenile idiopathic arthritis (JIA) is a clinical syndrome of various manifestations, characterized by chronic synovitis of unknown etiology constitutional and environmental factors clearly influence the debut and evolution of JIA. The main symptoms are fever and various arthropathies, lasting for more than 6 weeks acute phase reactants and specific immune changes such as rheumatoid factor; antinuclear antibodies are also presents. Radiology changes allow pertinent diagnosis, therapy and prognosis. Non-steroid anti-inflammatory is the initial option in each JIA case: cortical steroids may complete it, as well as immune-suppressor, immune-modulation adapted to the clinical and progressive pattern of the disease. Biological treatment with anti-cytokines medication it is the modern way. A complete physical examination is a critical for the diagnosis of juvenile idiopathic arthritis. Physical findings are important to provide criteria for diagnosis and to detect abnormalities suggestive of alternative etiologies for arthritis. The diagnosis of juvenile idiopathic arthritis is based on the physical finding of arthritis in at least one joint that persists for at least 6 weeks, with other causes excluded, in an individual younger than 16 years. No diagnostic serological tests for juvenile idiopathic arthritis are noted.In this case the authors present the treatment with Etanercept – anti-TNF-alpha – Embrel to the children. The author emphasize that the evolution in specific case of JIA is closely related to the patients biologic background the treatment and the clinical form of disease.
Keywords: juvenile idiopathic arthritis, anti-TNF-alpha, Etanercept
Presentation type: Oral
Correspondence: no. 1-3 Spitalului Sq., Arad, Romania
Email: vioricaleordean@yahoo.com