CORRELATIONS BETWEEN LEFT VENTRICULAR EJECTION FRACTION REDUCTION AND HEART RATE VARIABILITY

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Article Title:	CORRELATIONS BETWEEN LEFT VENTRICULAR EJECTION FRACTION REDUCTION AND HEART RATE VARIABILITY
Authors:	Cristiana Buştea1, Delia Mirela Ţiţ2*, Simona Bungău2, Cristian Sava3, Cristian Gheorghe Furău4, Anca Maria Sabău5, Cristian Buştea6
Affiliation:	1Preclinical disciplines Department, Faculty of Medicine and Pharmacy, University of Oradea, Oradea 2Pharmacy Department, Faculty of Medicine and Pharmacy, University of Oradea, Oradea 3Medical Disciplines Department, Faculty of Medicine and Pharmacy, University of Oradea, Oradea 4Life Sciences Department, Faculty of Medicine, Western University “Vasile Goldiş” of Arad, Arad 5Department of Physical Education, Sport and Kinetotherapy, Faculty of Geography, Tourism and Sport, University of Oradea, Oradea 6Surgical Disciplines Department, Faculty of Medicine and Pharmacy, University of Oradea, Oradea
Abstract:	The decrease of heart rate variability after acute myocardial infarction has been proved to be a predictor of both sudden death from any cause and sudden cardiac death. Decreased left ventricle ejection fraction is a negative prognostic factor in patients with acute myocardial infarction. Considering this, we intended to prove that there is a correlation between the decrease in the sinus rhythm variability and the degree of reduction of the left ventricle ejection fraction. We measured seven time domain parameters of heart rate variability in patients with acute myocardial infarction (7-10 days after the onset of the infarction; and low ejection fraction of the left ventricle. Parameters of the heart rate variability decreased progressively with the decrease of left ventricle ejection fraction. For patients with LVEF<20%, the decrease of the parameters was statistically significant. The inclusion of patients with severely altered systolic function among acute myocardial infarction surviving patients may alter the prognostic value of heart rate variability indices.
Keywords:	heart rate variability, left ventricular ejection fraction, prognostic factor, sinus rhythm variability.
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*Correspondence:	Delia Mirela Tit, University of Oradea Faculty of Medicine and Pharmacy, Department of Pharmacy N. Jiga, 29, 410028, Oradea, Romania, Tel. +4 0742 963 812, email: mirela_tit@yahoo.com