ECOCARDIOGHAPHIC DATA IN HEART FAILURE PATIENTS WITH PRESERVED EJECTION FRACTION TREATED WITH DOXORUBICIN

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Article Title:	ECOCARDIOGHAPHIC DATA IN HEART FAILURE PATIENTS WITH PRESERVED EJECTION FRACTION TREATED WITH DOXORUBICIN
Authors:	1ADINA POP-MOLDOVAN, 1MIHAI-NELU TROFENCIUC, 1MARIA PUŞCHIŢĂ
Affiliation:	Faculty of Medicine, Pharmacy and Dental Medicine, “Vasile Goldiş” Western University of Arad Romania
Abstract:	Echocardiography is considered to be a top noninvasive method for monitoring current patients on chemotherapy. The purpose of this study was to determine optimal timing of cardiac function monitoring and the risk factors for early induced doxorubicin cardiotoxicity by echocardiographic monitoring a 50 consecutive patients group with oncological pathology undergoing Doxorubicin chemotherapy. Because early detection of cardiac involvement would be useful in order to prevent progression to intractable heart failure, into our study group these determinations leaded to anthracycline treatment interruption and start of heart failure treatment. Also, we recommend a strict monitoring including a 3 months follow-up after the initiation of therapy with doxorubicin, not just at 6 weeks or at 6 months; we find this protocol necessary to early prevent cardiotoxicity elements and to intervene where necessary.
Keywords:	anthracycline, echocardiography, doxorubicin, cardiotoxicity, cardiomyopathy
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*Correspondence:	Pop-Moldovan Adina Faculty of Medicine, Pharmacy and Dental Medicine “VasileGoldiş” Western University of Arad, Romania Arad, 86 Liviu Rebreanu St. E-mail: ppmldvn68@yahoo.com