ALBUMINOTHERAPY AND HEPARINOTHERAPY RESISTANCE IN EXTENDED ENTERO-MEZENTERIC ISCHEMIA (CLINICAL CASE)

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Article Title:	ALBUMINOTHERAPY AND HEPARINOTHERAPY RESISTANCE IN EXTENDED ENTERO-MEZENTERIC ISCHEMIA (CLINICAL CASE)
Authors:	NICOLESCU CRISTIAN MIRCEA1,2, NICOLESCU LAURA1,2, TURLE LAVINIA1, PANTEA VETURIA ELISABETA 1,2 , MOLDOVAN SILVIU2 , POP ALEXANDRU1, DAMIAN GRATIAN1
Affiliation:	1„Vasile Goldis” West University of Arad, 2Arad County Emergency Hospital
Abstract:	We present a case for a patient, age 82, for which a surgical emergency intervention was undertaken, preoperative diagnosis was acute occlusive abdomen. Surgery revealed extended intestinal loop necrosis patient went enlarged enterectomy. After surgery heparin is administered, 5000IU initially bolus, then slow continuous intravenous using the injectomat, the administered doses requiring continuous incremental increases to get the hypocoagulation desired status. After 48 hours from starting treatment, the phenomenon of resistance to heparin was considered, intervention with fresh frozen plasma (without stopping the heparin therapy) was undertaken, afterwards patient evolution being subsequently favorable both in terms of clinical condition and laboratory data.
Keywords:	heparin, antithrombin III, activated prothrombin time, albumin
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