Portal hypertension in cirrhosis-staging and evolution of esophageal varices


Abstract Title: Portal hypertension in cirrhosis-staging and evolution of esophageal varices
Authors: Elena Magopat, Olivia Onorica Opris, Ioana Haiduc, Carmen Maler, Bogdan Miutescu, Eftimie Miutescu
Affiliation: “Vasile Goldis” Western University, Arad, Romania
Abstract text: Background: Hepatic cirrhosis is the most common cause of portal hypertension. In normal conditions the pressure between portal vein and inferior cave vein is about 2-6 mmHg. A significant portal hypertension appears when the pressure goes over 10 mmHg. Secondly to portal hypertension it devolves esophageal varices. Almost 50% of patients with hepatic cirrhosis devolve esophageal varices; and at third of these patients it can be complicated with severe superior digestive hemorrhage. Hemorrhagic esophageal varices have the biggest morbidity and mortality rate of any cause that can result with superior digestive hemorrhage. Aim: The aim of the study is to evidence the repartition on age and sex groups of hepatic cirrhosis and to establish a correlation with esophageal varices degree. Material and methods: The study evaluated 183 patients (63.4% men and 36.6% women) from Arad Clinical Hospital between the period of April 2009 – April 2010.There has been made a selection by following criteria: sex, group of age, the presence/absence of esophageal varices, the stage o esophageal varices such as the presence/absence of superior digestive hemorrhage caused by varices. Results and conclusions: The results are: From 183 patients diagnosed with hepatic cirrhosis 23.4% (41) were without esophageal varices, 24.7% (45) had esophageal varices stage I, 4.91% (9) was stage ½, 29.3 (50) was stage II,16.8% was stage III.
The incidence of esophageal varices goes up by age the most cases being between age group 50-59 years old at men such as women. In the case of superior digestive hemorrhage diagnosed on 30 patients a higher incidence was registered in men 73.3% (22) the cause being rupture of esophageal varices of IIIrd stage 58.6% (17).
Keywords: portal hypertension, esophageal varices
Presentation type: Oral
Correspondence: no. 1 Feleacului St., Arad, Romania
Email: elena_mgp@yahoo.com