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Title: Jurnal Medical Aradean (Arad Medical Journal)
Abbreviated title: J. Med. Ar.
Publisher: "Vasile Goldis" University Press
Owner: Western University "Vasile Goldis" Arad, Romania
ISSN: 1224-3744
e-ISSN: 2067-7790

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MEDIASTINAL SARCOIDOSIS MASS REVEALED BY PROGRESSIVE DYSPHAGIA – CASE REPORT PDF Print E-mail

MEDIASTINAL SARCOIDOSIS MASS REVEALED BY PROGRESSIVE DYSPHAGIA – CASE REPORT

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Title:MEDIASTINAL SARCOIDOSIS MASS REVEALED BY PROGRESSIVE DYSPHAGIA – CASE REPORT
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Article_Title:MEDIASTINAL SARCOIDOSIS MASS REVEALED BY PROGRESSIVE DYSPHAGIA – CASE REPORT
Authors:Ion Dina1, Octav Ginghina2*, Razvan Iosifescu2, George Traian Alexandru Burcea Dragomiroiu3, Corina Dalia Toderescu4, Geoge Ciprian Pribac5,6, Bianca Galateanu7, Cristian Balalau8, Claudia Gutu7, Carolina Negrei9
Affiliation:1“St. John Emergency Hospital” Bucharest, Gastroenterology- 2nd Medical Clinic, University of Medicine and Pharmacy “ Carol Davila”, Bucharest
2“St. John Emergency Hospital” Bucharest, Surgical Clinic, University of Medicine and Pharmacy “ Carol Davila”, Bucharest
3Department of Drug Control, “Carol Davila” University of Medicine and Pharmacy, 6, Traian Vuia Street, Bucharest, Romania
4Faculty of Pharmacy, Department of Pharmaceutical Sciences, ”Vasile Goldis” Western University of Arad, 91-93, L. Rebreanu Street, Arad, Romania
5 Faculty of Medicine, Department of Cell and Molecular Biology, Life Sciences Institute, ”Vasile Goldis” Western University of Arad, 91-93, L. Rebreanu Street, Arad, Romania
6 Department of Histopathology, Clinical Emergency County Hospital Arad, Romania
7Department of Biochemistry and Molecular Biology, University of Bucharest, Bucharest, Romania
8“Sf. Pantelimon” Hospital Bucharest, Surgical Clinic, “Carol Davila” University of Medicine and Pharmacy, 340-342, Pantelimon Street, Bucharest, Romania
9Department of Toxicology, “Carol Davila” University of Medicine and Pharmacy, 6, Traian Vuia Street, Bucharest, Romania
Abstract:Dysphagia is considered a digestive symptom caused not only by intrinsic gastrointestinal diseases, but also by extradigestive conditions. The mechanism of progressive dysphagia encountered in extraluminal esophageal diseases is related to extrinsic esophageal compression. Besides intraesophageal pathology responsible for dysphagia development, there have been described several causes, less frequently encountered in clinical practice: mediastinal tumors or masses of different etiologies, pericardial effusion, surgical changes, vascular compression. We report a case of sarcoidosis expressed by a giant posterior mediastinal lymphadenopathy that presented in a gastroenterology clinic for progressive dysphagia.
Keywords:dysphagia – mediastinal, mass- sarcoidosis, mediastinal lymphadenopathy
References:1. Adeyemie L, Reza Shaker, Esophageal Dysphagia. Phys Med Rehabil Clin N Am 19 (2008) 729-745
2. Giovinale M, Fonnesu C, Soriano A et al., Atypical sarcoidosis: case report and review of the literature. Eur Rev Med Pharmacol Sci 2009 Mar; 13 Suppl 1:37-44.
3. Guideline, Role of EUS for the evaluation of mediastinal adenopathy. Vol 74 no2:2011 Gastrointestinal Endoscopy. doi:10.1016/j.gie.2011.03.1255
4. Hemender Singh Vats, Dysphagia from extrinsic compression of esophagus by pericardial effusion. Clin Med Res. Sep 2008; 6(2): 78–79. doi: 10.3121/cmr.2008.780
5. Iannuzzi MC, Rybicki BA, Teirstein AS., Sarcoidosis, N Engl J Med 2007; 357:2153-2165. doi: 10.1056/NEJMra071714
6. Lemos EM, Santoro PP, Tavares RA et al., Oropharyngeal dysphagia in dermatomyosites: case report and literature review. Braz J Otorhinolaryngol. 2008 Nov-Dec;74(6):938-40.
7. Lind CD, Dysphagia: evaluation and treatment. Gastroenterol Clin North Am. 2003 Jun;32(2):553-575
8. Riedel RF, Burfeind WR., Thymoma: benign appearance, malignant potential. Oncologist 2006 Sep;11(8):887-94.
9. Saenz NC, Schnitzer JJ, Eraklis AE et al., Posterior mediastinal masses. J Pediatr Surj. 1993 Feb;28(2):172-176.
10. Siew Le Chong, Sing Ming Chao, An unsual cause of mediastinal mass – a case report and literature review of intrathoracic kidney. Proceedings of Singapore Healthcare; volume 21; number 2;2012
11. Singhal S, Hasan SS, Cohen DC et al., Multi-disciplinary approach for management of refractory benign occlusive esophageal strictures. Therap Adv Gastroentrol Sep 2013;6(5):365-370. doi: 10.1177/1756283X13492000
12. Yetim T D, Buyukkarabacak Y B, Bayarougullari et al., Rare causes of dysphagia; Mediastinal vascular anomalies. Global Advanced Research Journal of Medicine and Medical Sciences Vol. 1(3) pp. 057-060, April, 2012.
Read_full_article:pdf/vol19/iss4/5 JMA 2016 - Dina - Articol_Arad_22.06.2017_3.pdf
Correspondence:Octav Ginghina, “Sf. Ioan” Emergency Hospital, Surgical Clinic, University of Medicine and Pharmacy “ Carol Davila”, 13, Vitan-Bârzesti Street, 042122, Bucharest, Romania, +40213345170/+40213345970, email: This e-mail address is being protected from spambots. You need JavaScript enabled to view it
Read full article
Article Title:MEDIASTINAL SARCOIDOSIS MASS REVEALED BY PROGRESSIVE DYSPHAGIA – CASE REPORT
Authors:Ion Dina1, Octav Ginghina2*, Razvan Iosifescu2, George Traian Alexandru Burcea Dragomiroiu3, Corina Dalia Toderescu4, Geoge Ciprian Pribac5,6, Bianca Galateanu7, Cristian Balalau8, Claudia Gutu7, Carolina Negrei9
Affiliation:1“St. John Emergency Hospital” Bucharest, Gastroenterology- 2nd Medical Clinic, University of Medicine and Pharmacy “ Carol Davila”, Bucharest
2“St. John Emergency Hospital” Bucharest, Surgical Clinic, University of Medicine and Pharmacy “ Carol Davila”, Bucharest
3Department of Drug Control, “Carol Davila” University of Medicine and Pharmacy, 6, Traian Vuia Street, Bucharest, Romania
4Faculty of Pharmacy, Department of Pharmaceutical Sciences, ”Vasile Goldis” Western University of Arad, 91-93, L. Rebreanu Street, Arad, Romania
5 Faculty of Medicine, Department of Cell and Molecular Biology, Life Sciences Institute, ”Vasile Goldis” Western University of Arad, 91-93, L. Rebreanu Street, Arad, Romania
6 Department of Histopathology, Clinical Emergency County Hospital Arad, Romania
7Department of Biochemistry and Molecular Biology, University of Bucharest, Bucharest, Romania
8“Sf. Pantelimon” Hospital Bucharest, Surgical Clinic, “Carol Davila” University of Medicine and Pharmacy, 340-342, Pantelimon Street, Bucharest, Romania
9Department of Toxicology, “Carol Davila” University of Medicine and Pharmacy, 6, Traian Vuia Street, Bucharest, Romania
Abstract:Dysphagia is considered a digestive symptom caused not only by intrinsic gastrointestinal diseases, but also by extradigestive conditions. The mechanism of progressive dysphagia encountered in extraluminal esophageal diseases is related to extrinsic esophageal compression. Besides intraesophageal pathology responsible for dysphagia development, there have been described several causes, less frequently encountered in clinical practice: mediastinal tumors or masses of different etiologies, pericardial effusion, surgical changes, vascular compression. We report a case of sarcoidosis expressed by a giant posterior mediastinal lymphadenopathy that presented in a gastroenterology clinic for progressive dysphagia.
Keywords:dysphagia – mediastinal, mass- sarcoidosis, mediastinal lymphadenopathy
References:1. Adeyemie L, Reza Shaker, Esophageal Dysphagia. Phys Med Rehabil Clin N Am 19 (2008) 729-745
2. Giovinale M, Fonnesu C, Soriano A et al., Atypical sarcoidosis: case report and review of the literature. Eur Rev Med Pharmacol Sci 2009 Mar; 13 Suppl 1:37-44.
3. Guideline, Role of EUS for the evaluation of mediastinal adenopathy. Vol 74 no2:2011 Gastrointestinal Endoscopy. doi:10.1016/j.gie.2011.03.1255
4. Hemender Singh Vats, Dysphagia from extrinsic compression of esophagus by pericardial effusion. Clin Med Res. Sep 2008; 6(2): 78–79. doi: 10.3121/cmr.2008.780
5. Iannuzzi MC, Rybicki BA, Teirstein AS., Sarcoidosis, N Engl J Med 2007; 357:2153-2165. doi: 10.1056/NEJMra071714
6. Lemos EM, Santoro PP, Tavares RA et al., Oropharyngeal dysphagia in dermatomyosites: case report and literature review. Braz J Otorhinolaryngol. 2008 Nov-Dec;74(6):938-40.
7. Lind CD, Dysphagia: evaluation and treatment. Gastroenterol Clin North Am. 2003 Jun;32(2):553-575
8. Riedel RF, Burfeind WR., Thymoma: benign appearance, malignant potential. Oncologist 2006 Sep;11(8):887-94.
9. Saenz NC, Schnitzer JJ, Eraklis AE et al., Posterior mediastinal masses. J Pediatr Surj. 1993 Feb;28(2):172-176.
10. Siew Le Chong, Sing Ming Chao, An unsual cause of mediastinal mass – a case report and literature review of intrathoracic kidney. Proceedings of Singapore Healthcare; volume 21; number 2;2012
11. Singhal S, Hasan SS, Cohen DC et al., Multi-disciplinary approach for management of refractory benign occlusive esophageal strictures. Therap Adv Gastroentrol Sep 2013;6(5):365-370. doi: 10.1177/1756283X13492000
12. Yetim T D, Buyukkarabacak Y B, Bayarougullari et al., Rare causes of dysphagia; Mediastinal vascular anomalies. Global Advanced Research Journal of Medicine and Medical Sciences Vol. 1(3) pp. 057-060, April, 2012.
*Correspondence:Octav Ginghina, “Sf. Ioan” Emergency Hospital, Surgical Clinic, University of Medicine and Pharmacy “ Carol Davila”, 13, Vitan-Bârzesti Street, 042122, Bucharest, Romania, +40213345170/+40213345970, email: This e-mail address is being protected from spambots. You need JavaScript enabled to view it