Prophylaxis of infective endocarditis in dental procedures


Abstract Title: Prophylaxis of infective endocarditis in dental procedures
Authors: T. Jecherean, L. Moş, A. Marian, A.S. Marian
Affiliation: Vasile Goldis” Western University of Arad, Romania
Abstract text: Infective endocarditis is infection of the endocardium, usually with bacteria. The most frequently isolated aerobic bacteria in postdental procedures bacteraemia are StreptococcusViridans, even so, other periodontal pathogenic anaerobic bacteria are found in blood cultures. Major predisposing factors are congenital heart defects, rheumatic valvular disease, bicuspid or calcific aortic valves, mitral valve prolapse, and hypertrophic cardiomyopathy. The AHA Guidelines in Prevention of the Infective Endocarditis (IE) concluded that only an extremely small number of cases of IE might be prevented by antibiotic prophylaxis for dental procedures even if such prophylactic therapy were 100% effective; IE prophylaxis for dental procedures should be recommended only for patients with underlying cardiac conditions associated with the highest risk of adverse outcome from IE; for these patients, prophylaxis is recommended for all dental procedures that involve manipulation of gingival tissue or the periapical region of teeth or perforation of the oral mucosa. Dental pathogenic bacteria do not show to be covered by standard amoxicillin or clindamycin prophylactic regimens. Existing studies consider that the use of Amoxicillin/Clavulanic acid is the most appropriate option for prophylaxis of infective endocarditis associated with bacteraemia of oral origin.
Keywords: infective endocarditis, amoxicillin/clavulanic acid, dental procedures
Presentation type: Oral
Correspondence:  
Email: tavijecherean@yahoo.com