New concepts in primary open-angle glaucoma etiopathogenesis
| Abstract Title: | New concepts in primary open-angle glaucoma etiopathogenesis |
| Authors: | Flavia Marza |
| Affiliation: | “Vasile Goldis” Western University of Arad, Romania Clinical City Hospital, Arad, Romania |
| Abstract text: | Glaucoma is a multifactorial optic neuropathy being the second cause of blindness in the world. Our knowledge about vascular risk factors which are involved in physiopathology of glaucoma has progressed significantly in recent years. The elevated intraocular pressure was considered the prime factor responsible for the glaucomatous optic neuropathy involving death of retinal ganglion cells and their axons but despite the ability of modern treatments to lower the intraocular pressure, the disease continues to progress in many patients. There are clinical and experimental evidence that hemodynamic factors such as blood pressure, low diastolic perfusion pressure, heart disease and vasospastic syndrome (migraine, Raynaud’s syndrome) plays an important role in damage of optic nerve fiber layers. Examination of vascular risk profile is necessary in order to tailor the therapy to the patients individual need. This review try to summarize the current concepts in the pathophysiology of glaucoma. |
| Keywords: | glaucoma, vascular risk factors, blood pressure, pathophysiology |
| Presentation type: | Oral |
| Correspondence: | no. 1 Tudor Vladimirescu St., Arad, Romania |
| Email: | flavia_marza@yahoo.com |
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