Manifestari clinice in lacunarismul cerebral

Manifestari clinice in lacunarismul cerebral

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Title: Manifestari clinice in lacunarismul cerebral
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Article_Title: Manifestari clinice in lacunarismul cerebral
Authors: Sanda Maria Deme1, Cătălin D. Jianu2, Pavel Dan Nanu1
Affiliation: 1 Department of Neurology, “Vasile Goldis” Western University, Arad, Romania
2 Department of Neurology, University of Medicine and Pharmacy „Victor Babes” Timisoara, Romania
Abstract: CLINICAL TRAITS IN LACUNAR STROKE. Cerebral lacunar infarcts next to leukoaraiosis are members of the so called silent strokes family. The aetiology and the clinics are less known because the diagnosis is an accidental one. The first contact with a lacunary patient is usually at the general practitioner’s office. The patient will be later diagnosed by the neurologist using, and later differed to the general practitioner that will continue the therapy for such a patient. This scientific paper is willing to explain the aetiology, the morphopathology and the clinics of the lacunar infarcts for a better understanding of the lacunary patient concept.
Keywords: lacunar stroke, clinical traits, aetiology, morphopathology
References: AMARENCO P, COHEN A, TZOURIO C, BERTRAND B, HOMMEL M, BESSON G, CHAUVEL C, TOUBOUL J, BOUSSER M. Atherosclerotic disease of the aortic arch and the risk of ischemic stroke. N Engl J Med. 1994; 331: 1474–1479.
BAUMGARTNER RW, ARNOLD M, GÖNNER F, STAIKOW I, HERRMANN C, RIVOIR A, MÜRI RM. Contrast-enhanced transcranial color-coded duplex sonography in ischemic cerebrovascular disease. Stroke. 1997; 28: 2473–2478.
BAUMGARTNER RW, BAUMGARTNER I, MATTLE HP, SCHROTH G. Transcranial color-coded duplex sonography in the evaluation of collateral flow through the circle of Willis. AJNR Am J Neuroradiol. 1997; 18: 127–133.
BOITEN J, LUIJCKX GJ, KESSELS F, LODDER J. Risk factors for lacunes. Neurology. 1996; 47: 1109–1110.
CHAMORRO A, SAIZ A, VILA N, ASCASO C, BLANC R, ALDAY M, PUJOL J. Contribution of arterial blood pressure to the clinical expression of lacunar infarction. Stroke. 1996; 27: 388–392.
DE BRAY JM, GLATT B. Quantification of atheromatous stenosis in the extracranial internal carotid artery. Cerebrovasc Dis. 1995; 5: 414–426.
FISHER CM, CURRY HB. Pure motor hemiplegia from vascular origin. Arch Neurol. 1965; 13: 30–44.
FISHER CM. A lacunar stroke: the dysarthria-clumsy hand syndrome. Neurology. 1967; 17: 614–617.
GAN R, SACCO RL, KARGMAN DE, ROBERTS JK, BODEN-ALBALA B, GU Q. Testing the validity of the lacunar hypothesis: the Northern Manhattan Stroke Study experience. Neurology. 1997; 48: 1204–1211.
LAMMIE GA, WARDLAW JM. Small centrum semiovale infarcts: a pathological study. Cerebrovasc Dis. 1999; 9: 82–90.
LANDI G, CELLA E, BOCCARDI E, MUSICCO M. Lacunar versus nonlacunar infarcts: pathogenetic and prognostic differences. J Neurol Neurosurg Psychiatry. 1992; 55: 441–445.
MATTLE HP, GROLIMUND P, HUBER P, STURZENEGGER M, ZURBRÜGG H. Transcranial Doppler sonographic findings in middle cerebral artery disease. Arch Neurol. 1988; 45: 289–295.
MONCAYO J, DEVUYST G, VAN MELLE G, BOGOUSSLAVSKY J. Coexisting causes of ischemic stroke. Arch Neurol. 2000; 57: 1139–1144.
VON BÜDINGEN HJ, VON REUTERN GM. Ultraschalldiagnostik der hirnversorgenden Arterien. Stuttgart, Germany: Thieme; 1993.
WILTERDINK JL, BENDIXEN B, ADAMS HP JR, WOOLSON RF, CLARKE WR, D HM, for the TOAST Investigators. Effect of prior aspirin use on stroke severity in the Trial of Org 10172 in Acute Stroke Treatment (TOAST). Stroke. 2001; 32: 2836–2840.
WITYK RJ, PESSIN MS, KAPLAN RF, CAPLAN LR. Serial assessment of acute stroke using the NIH Stroke Scale. Stroke. 1994; 25: 362–365.
Read_full_article: pdf/vol12/iss2/JMA12-2-09Deme.pdf
Correspondence: Sanda Maria Deme, MD, PHD, Department of Neurology, „Vasile Goldis” Western University of Arad, 94-96 Revolutiei Bd., Arad, Romania, Tel: +40-257-212204; E-mail: sandademe@yahoo.com

Read full article
Article Title: Manifestari clinice in lacunarismul cerebral
Authors: Sanda Maria Deme1, Cătălin D. Jianu2, Pavel Dan Nanu1
Affiliation: 1 Department of Neurology, “Vasile Goldis” Western University, Arad, Romania
2 Department of Neurology, University of Medicine and Pharmacy „Victor Babes” Timisoara, Romania
Abstract: CLINICAL TRAITS IN LACUNAR STROKE. Cerebral lacunar infarcts next to leukoaraiosis are members of the so called silent strokes family. The aetiology and the clinics are less known because the diagnosis is an accidental one. The first contact with a lacunary patient is usually at the general practitioner’s office. The patient will be later diagnosed by the neurologist using, and later differed to the general practitioner that will continue the therapy for such a patient. This scientific paper is willing to explain the aetiology, the morphopathology and the clinics of the lacunar infarcts for a better understanding of the lacunary patient concept.
Keywords: lacunar stroke, clinical traits, aetiology, morphopathology
References: AMARENCO P, COHEN A, TZOURIO C, BERTRAND B, HOMMEL M, BESSON G, CHAUVEL C, TOUBOUL J, BOUSSER M. Atherosclerotic disease of the aortic arch and the risk of ischemic stroke. N Engl J Med. 1994; 331: 1474–1479.
BAUMGARTNER RW, ARNOLD M, GÖNNER F, STAIKOW I, HERRMANN C, RIVOIR A, MÜRI RM. Contrast-enhanced transcranial color-coded duplex sonography in ischemic cerebrovascular disease. Stroke. 1997; 28: 2473–2478.
BAUMGARTNER RW, BAUMGARTNER I, MATTLE HP, SCHROTH G. Transcranial color-coded duplex sonography in the evaluation of collateral flow through the circle of Willis. AJNR Am J Neuroradiol. 1997; 18: 127–133.
BOITEN J, LUIJCKX GJ, KESSELS F, LODDER J. Risk factors for lacunes. Neurology. 1996; 47: 1109–1110.
CHAMORRO A, SAIZ A, VILA N, ASCASO C, BLANC R, ALDAY M, PUJOL J. Contribution of arterial blood pressure to the clinical expression of lacunar infarction. Stroke. 1996; 27: 388–392.
DE BRAY JM, GLATT B. Quantification of atheromatous stenosis in the extracranial internal carotid artery. Cerebrovasc Dis. 1995; 5: 414–426.
FISHER CM, CURRY HB. Pure motor hemiplegia from vascular origin. Arch Neurol. 1965; 13: 30–44.
FISHER CM. A lacunar stroke: the dysarthria-clumsy hand syndrome. Neurology. 1967; 17: 614–617.
GAN R, SACCO RL, KARGMAN DE, ROBERTS JK, BODEN-ALBALA B, GU Q. Testing the validity of the lacunar hypothesis: the Northern Manhattan Stroke Study experience. Neurology. 1997; 48: 1204–1211.
LAMMIE GA, WARDLAW JM. Small centrum semiovale infarcts: a pathological study. Cerebrovasc Dis. 1999; 9: 82–90.
LANDI G, CELLA E, BOCCARDI E, MUSICCO M. Lacunar versus nonlacunar infarcts: pathogenetic and prognostic differences. J Neurol Neurosurg Psychiatry. 1992; 55: 441–445.
MATTLE HP, GROLIMUND P, HUBER P, STURZENEGGER M, ZURBRÜGG H. Transcranial Doppler sonographic findings in middle cerebral artery disease. Arch Neurol. 1988; 45: 289–295.
MONCAYO J, DEVUYST G, VAN MELLE G, BOGOUSSLAVSKY J. Coexisting causes of ischemic stroke. Arch Neurol. 2000; 57: 1139–1144.
VON BÜDINGEN HJ, VON REUTERN GM. Ultraschalldiagnostik der hirnversorgenden Arterien. Stuttgart, Germany: Thieme; 1993.
WILTERDINK JL, BENDIXEN B, ADAMS HP JR, WOOLSON RF, CLARKE WR, D HM, for the TOAST Investigators. Effect of prior aspirin use on stroke severity in the Trial of Org 10172 in Acute Stroke Treatment (TOAST). Stroke. 2001; 32: 2836–2840.
WITYK RJ, PESSIN MS, KAPLAN RF, CAPLAN LR. Serial assessment of acute stroke using the NIH Stroke Scale. Stroke. 1994; 25: 362–365.
*Correspondence: Sanda Maria Deme, MD, PHD, Department of Neurology, „Vasile Goldis” Western University of Arad, 94-96 Revolutiei Bd., Arad, Romania, Tel: +40-257-212204; E-mail: sandademe@yahoo.com