HER-2 / neu Expression in assesment of the oncogene risk of ulcerative colitis

January 28, 2016

HER-2 / neu Expression in assesment of the oncogene risk of ulcerative colitis

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Title:	HER-2 / neu Expression in assesment of the oncogene risk of ulcerative colitis
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Article_Title:	HER-2 / neu Expression in assesment of the oncogene risk of ulcerative colitis
Authors:	Florinel Cozma1, Marius Raica2, Carmen Neamtu1, Totolici Bogdan1
Affiliation:	1 Western University “Vasile Goldis” Arad 2 University of Medicine and Pharmacy Timişoara
Abstract:	Human HER-2 gene encodes a protein that is a membrane receptor for epidermal growth factor. Most studies on the HER-2 had bladder cancer and breast object. We have questioned whether overexpression of HER-2 / neu may be observed in patients with UC, and found that this protein has individual prognostic value at pacients with active UC.
Keywords:	colitis, bladder cancer, HER-2, breast object, malignant tumors
References:	Sternberg S.S, Histology for pathologists, Raven-Lippicot 2002 Grigorescu M, Pascu O, Gastroenerology Treaty, Ed. Tehnica 1996 Cozma F, Research Reguarding The Cancer Risk in Ulcerative Colitis, PhD thesis 2003 Laurent Beaugerie, M.D., Ph.D., and Steven H. Itzkowitz, M.D. Cancers Complicating Inflammatory Bowel Disease N Engl J Med 2015; 372:1441-1452April 9, 2015DOI: 10.1056/NEJMra1403718
Read_full_article:	pdf/vol18/iss2/12 JMA 2015 – Cosma – HER2 neu Expression.pdf
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Article Title:	HER-2 / neu Expression in assesment of the oncogene risk of ulcerative colitis
Authors:	Florinel Cozma1, Marius Raica2, Carmen Neamtu1, Totolici Bogdan1
Affiliation:	1 Western University “Vasile Goldis” Arad 2 University of Medicine and Pharmacy Timişoara
Abstract:	Human HER-2 gene encodes a protein that is a membrane receptor for epidermal growth factor. Most studies on the HER-2 had bladder cancer and breast object. We have questioned whether overexpression of HER-2 / neu may be observed in patients with UC, and found that this protein has individual prognostic value at pacients with active UC.
Keywords:	colitis, bladder cancer, HER-2, breast object, malignant tumors
References:	Sternberg S.S, Histology for pathologists, Raven-Lippicot 2002 Grigorescu M, Pascu O, Gastroenerology Treaty, Ed. Tehnica 1996 Cozma F, Research Reguarding The Cancer Risk in Ulcerative Colitis, PhD thesis 2003 Laurent Beaugerie, M.D., Ph.D., and Steven H. Itzkowitz, M.D. Cancers Complicating Inflammatory Bowel Disease N Engl J Med 2015; 372:1441-1452April 9, 2015DOI: 10.1056/NEJMra1403718
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