Influence of Diabetes mellitus on short term mortality in patients with first acute ST

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Article Title:	Influence of Diabetes mellitus on short term mortality in patients with first acute ST – Elevation myocardial infarction: a ten years retrospective study
Authors:	Calin Pop1,2, Lavinia Pop2, Mihaela Roman2, Delia Dan2, Daniela Dicu2
Affiliation:	1 “Vasile Goldis” Western University Arad, Romania 2 Emergency County Hospital Baia Mare, Romania
Abstract:	The objective was to compare short-term mortality after a first acute myocardial infarction with ST elevation (STEMI) in patients with and without diabetes mellitus (DM). Between 1.01.2000 – 31.12.2009, 1335 STEMI patients were admitted in the Baia Mare Emergency Hospital: 660 (142 DM) had no thrombolysis, 675 (136 DM) received thrombolysis. In-hospital mortality was 19.4% in the 278 DM patients and 14.3% in the 1057 non-DM patients (p=0.002). Mortality in the subgroups was different: 11.3% in the 539-thrombolysed non-DM patients, 16.5 % in the 136-DM thrombolysed patients (p=0.01) and 21.4% in 142 DM patients without thrombolysis (p<0.0001). DM patients had more failed thrombolysis, 5.8% vs. 2.1%, and more recurrent ischemia, 9.3 % vs. 4.6 %, than non-DM patients had (p=0.002). Short-term mortality after a first STEMI in DM patients is higher due to a worse clinical profile but also to a less effective myocardial reperfusion.
Keywords:	mortality, STEMI, diabetes mellitus, thrombolysis, myocardial reperfusion
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*Correspondence:	Calin Pop, Faculty of Medicine, Vasile Goldis Western University Arad, Str. Unirii nr. 3 Arad 310123 Romania, e-mail:medicbm@yahoo.com